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. 2013 Nov 26;8(11):e80204. doi: 10.1371/journal.pone.0080204

Figure 4. Allele specific expression (ASE) analysis with rs615470 in 15 frontal cortices of African ancestry.

Figure 4

4a. Davies-Bouldin (DB) validity index analysis. Columns represent the ASE. Dotted line represents the DB validity index. The red dot indicates the optimal d cutoff predicted by the DB index that coincides with ASE. 4b. Concordance of allelic expression variation with heterozygosity. Samples #1 to #5 which show relative allelic expression balance (*ASE<2) are homozygous for all 10 SNPs highlighted. Samples #6 to #15 which show relative allelic expression imbalance are heterozygous for all 10 SNPs. *See material and method for details; ASE: relative allele specific expression.