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The number of BDNF immunoreactive neurons was significantly higher in L6 DRG from animals treated with CYP and control IgG (A, C) when compared to those from animals treated with NGF neutralizing antibody and CYP (B, C). Blockade of NGF activity in cystitis animals also reduced BDNF transcription in the L6 DRG (D). *, p < 0.05 vs CYP+IgG. n=5 animals for each group. Bar=80 µm.
