Fig 1.

Detection of luciferase expression in the mouse liver after hydrodynamics-based gene delivery. NF-κB reporter gene expression in the livers (n=5) was monitored longitudinally through noninvasive molecular imaging (A, B). Serum ALT and AST levels at indicated time points were shown. n=5 in each group (C). Histological examination of tissue damage through HE staining of liver sections from mice at 1, 2, 3, and 6 days after the hydrodynamics-based gene delivery was shown. The results are representative of 3 experiments. Original magnification ×200 (D).