Percent change in mean arterial pressure (MAP) as measured by telemetry in control (CON)-, nifedipine (NIF)-, nifedipine in combination with spironolactone (NIF + SPR)-, nifedipine in combination with losartan (NIF + LOS)-, and enalapril (ENAL)-treated virgin female rats. A one-way repeated-measures ANOVA was performed. Values are presented as means ± SE. P < 0.05 vs. CON (*), NIF (§), NIF + SPR (†), NIF + LOS (£), and ENAL (‡).