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Mean data showing intracellular superoxide production at 1, 12, 24, and 36 h following NE (50 pg/ml, 50 ng/ml, and 50 μg/ml) treatment applied at 30 h. Also shown is mean data for superoxide production with the addition of DPI (NE + DPI) to block NADPH oxidase at 36 h. Data are expressed as fold change from control treatment (PBS only) at 1 h. *Significant difference vs. Control (P < 0.05; within time point). ‡Significant difference vs. NE at 36 h (P < 0.05).
