Table 1.
Control | Decompression | |
---|---|---|
No manipulations | 1.00 ± 0.04 (20) | 1.45 ± 0.15 (9)* |
+ PEG | 0.92 ± 0.03 (3) | 1.00 ± 0.03 (9) |
Thrombocytopenia | 1.05 ± 0.09 (3) | 1.13 ± 0.05 (3) |
+ 1400 W | 1.11 ± 0.02 (3) | 1.18 ± 0.04 (3) |
MPO-KO | 1.14 ± 0.05 (6) | 1.20 ± 0.07 (3) |
iNOS-KO | 1.02 ± 0.06 (3) | 1.18 ± 0.04 (3) |
Values were normalized to the mean wild-type mouse control action potential width (3.97 ± 0.14 ms) and are displayed as means ± SE (n = individual mice studied).Where shown wild-type mice were first rendered thrombocytopenic, injected with 25 mg/kg 1400 W immediately before pressure exposure or injected with PEG telomere B (PEG) after decompression and killed 1 h later. Knock-out (KO) mice used in some studies lacked myeloperoxidase (MPO) or iNOS.
P < 0.05.