Table 2.

Action potential width at half-maximum height for injected mice relative to mean value for control mice

Injection	No. of MPs Injected	Relative AP
PBS only	0	1.01 ± 0.03 (6)
Control mouse MPs	7.22 × 105 (± 19,123)	0.95 ± 0.05 (3)
Decompressed WT MPs	6.78 × 105 (± 29,025)	1.24 ± 0.02 (3)*
Decompressed iNOS KO MPs	8.59 × 105 (± 61,639)	1.33 ± 0.11 (3)*
Decompressed WT MPs + Nox2ds	7.04 × 105 (± 15,392)	1.25 ± 0.02 (4)*
Decompressed WT MPs + sham Nox2ds	7.26 × 105 (± 23,351)	1.49 ± 0.03 (4)*

Values are means ± SE; n = individual mice studied. The first column indicates source of microparticles (MPs) injected into naive mice. Mean numbers of MPs injected from different types of mice are shown in the second column (no significant difference among samples). Action potential (AP) width relative to the mean unmanipulated control mouse value (3.97 ± 0.14 ms) is shown in the third column. MPs were obtained from control wild-type (WT) mice not subjected to decompression stress, WT mice first subjected to 790 kPa air for 2 h, or iNOS KO mice first subjected to 790 kPa air pressure for 2 h. The last two rows show the effect of injecting MPs from WT mice first subjected to 790 kPa air pressure but incubated with 10 μM Nox2ds or a control scrambled sequence peptide during isolation.

^*P < 0.05.