Table 4.
KEGG pathway | IGSEA4GWAS P value | GSA-SNP P value |
---|---|---|
KEGG_CELL_ADHESION_MOLECULES_CAMS | <0.001 | 7.41 × 10−10 |
KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | <0.001 | 4.97 × 10−9 |
KEGG_CALCIUM_SIGNALING_PATHWAY | <0.001 | 1.09 × 10−8 |
KEGG_ECM_RECEPTOR_INTERACTION | <0.001 | 3.09 × 10−7 |
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | <0.001 | 1.30 × 10−5 |
KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS | <0.001 | 2.73 × 10−5 |
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | 0.003 | 3.84 × 10−5 |
KEGG_DILATED_CARDIOMYOPATHY | <0.001 | 7.91 × 10−5 |
KEGG_TYPE_I_DIABETES_MELLITUS | <0.001 | 8.58 × 10−5 |
KEGG_ALLOGRAFT_REJECTION | <0.001 | 0.0004 |
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES | <0.001 | 0.0004 |
KEGG_PPAR_SIGNALING_PATHWAY | <0.001 | 0.0004 |
KEGG_GRAFT_VERSUS_HOST_DISEASE | <0.001 | 0.0012 |
KEGG_VIRAL_MYOCARDITIS | <0.001 | 0.0015 |
KEGG_ADHERENS_JUNCTION | 0.008 | 0.0043 |
KEGG_PURINE_METABOLISM | 0.001 | 0.0046 |
All pathways have a false discovery rate of <5%.