Table 2. Multivariate logistic regression analysis for ECMO/death outcome for the entire study cohort and for the individual treatment groups.
| Variable | Odds ratio (95% CI) for ECMO/death | P-value |
|---|---|---|
| Entire cohort | ||
| Oxygenation index <20 | 0.52 (0.27–0.97) | 0.04 |
| Surfactant use | 0.47 (0.24–0.91) | 0.03 |
| Lung diseases relative to primary pulmonary hypertension | ||
| RDS | 0.22 (0.05–0.75) | 0.03 |
| Perinatal aspiration | 0.84 (0.41–1.75) | 0.63 |
| Pneumonia/sepsis | 0.49 (0.16–1.37) | 0.20 |
| Control group | ||
| Surfactant use | 0.27 (0.10–0.72) | 0.01 |
| Early iNO group | ||
| iNO at OI <20 relative to iNO at OI 20–25 | 0.25 (0.08–0.67) | 0.01 |
Abbreviations: CI, confidence interval; ECMO, extracorporeal membrane oxygenation; iNO, inhaled nitric oxide; OI, oxygenation index; RDS, respiratory distress syndrome.