Table 3. Effect of surfactant on the risk of ECMO/death for lung diseases associated with HRF among the entire study cohort consisting of both early inhaled nitric oxide and control groups.
| Diagnosis | ECMO/death for surfactant-treated group, n (%) | ECMO/death for the no surfactant group, n (%) | P-value | 
|---|---|---|---|
| Primary pulmonary hypertension | 12/42 (28.6) | 7/37 (19) | 0.43 | 
| RDS | 1/45 (2.2) | 2/7 (28.6) | 0.04 | 
| Perinatal aspiration syndrome | 11/79 (14) | 14/47 (30) | 0.04 | 
| Pneumonia/sepsis | 1/25 (4) | 5/16 (31) | 0.03 | 
| Lung diseases other than primary pulmonary hypertension | 14/150 (9.3) | 21/70 (30) | <0.001 | 
Abbreviations: ECMO, extracorporeal membrane oxygenation; HRF, hypoxic respiratory failure; RDS, respiratory distress syndrome.
Data are shown for babies who met ECMO/death outcome for each diagnosis, for surfactant-treated and untreated groups as number (n) and percent (%).