TABLE 2.
Pairwise comparison of mutant GNAS samples by grade of dysplasia, epithelial differentiation, and duct involvement
| Dysplasia grade | n | Mutant, n (%) |
|---|---|---|
| Low-grade dysplasia | 20 | 10 (50) |
| Intermediate-grade dysplasia | 19 | 12 (63) |
| P | 0.523 | |
| Intermediate-grade dysplasia | 19 | 12 (63) |
| High-grade dysplasia | 47 | 30 (64) |
| P | >0.99 | |
| Low-grade dysplasia | 20 | 10 (50) |
| High-grade dysplasia | 47 | 30 (64) |
| P | 0.415 | |
| Gastric | 53 | 27 (51) |
| Pancreatobiliary | 7 | 5 (71) |
| P | 0.432 | |
| Intestinal | 12 | 12 (100) |
| Pancreatobiliary | 7 | 5 (71) |
| P | 0.123 | |
| Oncocytic | 2 | 0 (0) |
| Pancreatobiliary | 7 | 5 (71) |
| P | 0.167 | |
| Intestinal | 12 | 12 (100) |
| Gastric | 53 | 27 (51) |
| P | 0.001 | |
| Oncocytic | 2 | 0 (0) |
| Gastric | 53 | 27 (51) |
| P | 0.491 | |
| Oncocytic | 2 | 0 (0) |
| Intestinal | 12 | 12 (100) |
| P | 0.011 | |
| Mixed duct | 9 | 5 (56) |
| Main duct | 30 | 18 (60) |
| P | >0.99 | |
| Branch duct | 37 | 21 (57) |
| Main duct | 30 | 18 (60) |
| P | 0.809 | |
| Branch duct | 37 | 21 (57) |
| Mixed duct | 9 | 5 (56) |
| P | >0.99 |
P values are for testing whether the proportion of mutated samples is different between patient groups