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. Author manuscript; available in PMC: 2013 Nov 27.
Published in final edited form as: Hypertension. 2011 Nov 7;59(1):10.1161/HYPERTENSIONAHA.111.173328. doi: 10.1161/HYPERTENSIONAHA.111.173328

Figure 1. IL-6 expression level is elevated in the kidneys of CKD patients and is further increased in CKD patients with hypertension.

Figure 1

(A) Immunohistochemistry study of IL-6 expression in control individuals with acute kidney rupture, CKD patients without and with hypertension. Microscopic examination revealed that IL-6 expression was significantly elevated in glomeruli and tubules of kidneys of CKD patients without hypertension and additionally elevated in CKD patients with hypertension. Scale bar=400 μM. (B) Semiquantitative analysis of IL-6 expression levels in the kidney biopsies from controls and CKD patients with or without hypertension. The average densities ± s.e.m. of 25 areas per kidney were determined. n = 15-48 kidneys for each category. * p<0.05 compared to control with acute kidney rupture, ** p<0.05 compared to CKD without hypertension.