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. Author manuscript; available in PMC: 2014 Nov 20.
Published in final edited form as: Neuron. 2013 Nov 20;80(4):10.1016/j.neuron.2013.10.008. doi: 10.1016/j.neuron.2013.10.008

Figure 1.

Figure 1

Changing views about dementia through the years. In the early 1900s vascular factors were thought to be the main cause of dementia. Over the next several decades Alzheimer’s disease was felt to be the main cause. Clinical-pathological studies have revealed that mixed dementia, combining feature of vascular dementia and AD, is currently the most common cause of cognitive impairment in the aged.