Table 1.
Frequency of MnPCE and mitotic activity (% PCE) in bone marrow cells of mice treated with CCT fruits extract and/or CP.
| Group | Treatment | % MnPCEa | % PCEa |
|---|---|---|---|
| 1 | Control | 0.54 ± 0.08 | 51.32 ± 6.21 |
| 2 | CP | 6.14 ± 0.36b | 32.48 ± 4.15b |
| 3 | CCT 10 mg/kg + CP | 5.94 ± 0.72d | 31.28 ± 7.85d |
| 4 | CCT 50 mg/kg + CP | 3.62 ± 0.81f | 40.62 ± 5.14f |
| 5 | CCT 100 mg/kg + CP | 1.04 ± 0.27c,e | 48.89 ± 6.78c,e |
| 6 | CCT 200 mg/kg + CP | 0.92 ± 0.06c,e | 50.32 ± 8.01c,e |
| 7 | CCT 200 mg/kg | 0.47 ± 0.14e | 51.79 ± 5.46e |
CCT: Citrullus colocynthis; CP: cyclophosphamide; MnPCE: micronucleated polychromatic erythrocyte.
aValues are the mean ± standard deviation for each group of 5 mice. b P < 0.0001 compared to the control; c P < 0.0001 compared with the CP treated group; f P < 0.001 compared with the CP treated group. dNo significant difference compared to the CP group. eNo significant difference compared to the control group.
The data were analyzed with one-way ANOVA and Tukey's HSD test.