Table 2.

Levels of MDA, GSH, GSSG, and GSH/GSSG ratio in bone marrow of mice after treatment with CCT (200 mg/kg) and/or CP (70 mg/kg).

Groups (mg/kg)	MDA (µmol/g protein)	GSH (µmol/g protein)	GSSG (µmol/g protein)	GSH/GSSG ratio
Control	0.74 ± 0.17	13.64 ± 4.36	3.38 ± 0.43	4.03 ± 1.07
CP	3.07 ± 0.42b	3.81 ± 1.47b	13.38 ± 3.76b	0.28 ± 0.05b
CCT	0.71 ± 0.32c	14.69 ± 5.16c	2.97 ± 0.35c	4.94 ± 1.72c
CCT + CP	1.32 ± 0.24d	12.37 ± 3.84e	6.14 ± 3.84d	2.01 ± 0.63d

CCT: Citrullus colocynthis; CP: cyclophosphamide; MDA: lipid peroxidation; GSH: reduced glutathione; GSSG: oxidized glutathione.

^aValues are the mean ± standard deviation for each group of 5 mice. ^b P < 0.0001 compared to the control. ^cNo significant difference compared to the control group; ^d P < 0.001 compared with the CP treated group;^e P < 0.0001 compared with the CP treated group.

The data were analyzed with one-way ANOVA and Tukey's HSD test.