Table 2.
Level of FGF2 release detected in coronary effluent during baseline, ischemia and reperfusion.
Wildtyoe | LMWKO | HMWKO | |
---|---|---|---|
Baseline (Equilibration) | 8.3±3.3 | not detected (ND) | 14.5±4.3 |
Ischemia (0–30 min) | ND | ND | ND |
Early Rep (0–14 min) | 10.6±4.0 | ND | 15.7±3.6 |
Late Rep (110–120 min) | 12.3±4.3 | ND | 16.8±7.1 |
Concentration (in pg/min/g heart weight) of FGF2 secreted in coronary effluent from wildtype, hearts deficient of the LMW isoform (LMWKO) and deficient of HMW isoforms (HMWKO) collected at baseline, ischemia and reperfusion (Rep). ND: not detected. n=4 per group.