TABLE 1.

CXCR4 Expression in Cerebral Brain Metastasis of Breast Cancer and Lung Cancer Samples

		CXCR4 expression in the carcinoma cells					CXCR4 expression in the adjacent gliosis
Tissue type	Total amount	0	+	++	+++	Total amount	0	+	++	+++
Breast cancer	23	3 (13.0%)	12 (52.2%)	6 (26.1%)	2 (8.7%)	15	3 (20.0%)	7 (46.7%)	4 (26.7%)	1 (6.6%)
Lung cancer	22	5 (22.7%)	13 (59.1%)	4 (18.2%)	0 (0%)	16	5 (31.2%)	8 (50%)	3 (18.8%)	0 (0%)

Human patient samples stained for CXCR4 with IHC in normal brain, lung, and breast cerebral metastasis samples. The metastasis samples were analyzed for CXCR4 expression in the carcinoma cells as well as in the gliosis zone if available.