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. Author manuscript; available in PMC: 2014 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2013 Jun 26;86(8):10.1016/j.bcp.2013.06.015. doi: 10.1016/j.bcp.2013.06.015

Figure 4.

Figure 4

Time course of ACh and ACh + ethanol modulation of DAergic neuron activity. The effects of A) ACh alone or B) with ethanol on average normalized AP frequency in WT and α6 KO VTA DAergic neurons under each condition are shown (from Figure 3). The effect of ACh with ethanol in the presence of α-CTX-MII[E11A] in WT VTA DAergic neurons is also shown (red circles). ACh ± ethanol was applied at the times indicated by the bar. Recording times between groups were aligned based on time of ethanol application to facilitate comparison.