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. Author manuscript; available in PMC: 2013 Nov 27.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Aug 12;21(20):10.1016/j.bmcl.2011.08.027. doi: 10.1016/j.bmcl.2011.08.027

Table 2.

IC50 values of SAHA and the C3-ethyl SAHA variant 1c for HDAC1, HDAC3, and HDAC6

Compounds IC50, µM [a]
HDAC1 HDAC3 HDAC6
SAHA 0.096 ± 0.016 0.146 ± 0.012 0.074 ± 0.009
1c 22 ± 2 97 ± 6 8 ± 1
[a]

Values are the mean of three experiments with standard error.