Table 2.
Association analysis of SNPs in COL15A1
| Controls |
Cases |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| tagSNP | PROBE | P-value | Odds ratio | Individuals assayed | Minor allele | Minor allele frequency (%) | Individuals assayed | Minor allele frequency | Minor allele frequency (%) |
| 1 | RS932670 | 0.103 | 0.714 | 275 | C | 14.7 | 214 | C | 11.9 |
| 2 | RS7874187 | 0.606 | 1.077 | 281 | G | 37.2 | 215 | G | 40.0 |
| 3 | RS12379516 | 0.681 | 1.100 | 281 | C | 10.1 | 223 | C | 11.7 |
| 4 | RS4743294 | 0.359 | 1.153 | 272 | A | 29.0 | 213 | A | 31.9 |
| 5 | RS10819454 | 0.165 | 1.480 | 282 | C | 6.4 | 220 | C | 8.0 |
| 6 | RS10819456 | 0.117 | 1.573 | 279 | T | 5.9 | 223 | T | 8.1 |
| 7 | RS7470221 | 0.131 | 0.810 | 281 | C | 47.9 | 221 | C | 46.2 |
| 8 | RS13288865 | 0.755 | 1.083 | 282 | G | 7.4 | 221 | G | 7.7 |
| 9 | RS17710605 | 0.876 | 0.961 | 276 | G | 9.2 | 216 | G | 7.9 |
| 10 | RS10819460 | 0.246 | 1.268 | 282 | C | 14.5 | 221 | C | 15.8 |
| 11 | RS17783501 | 0.247 | 0.842 | 274 | C | 37.6 | 212 | C | 36.1 |
| 12 | RS7045933 | 0.362 | 1.155 | 277 | T | 30.9 | 221 | T | 31.7 |
| 13 | RS6478963 | 0.487 | 1.112 | 280 | C | 29.8 | 221 | C | 31.7 |
| 14 | RS1413294 | 0.612 | 1.092 | 281 | G | 20.3 | 217 | G | 21.4 |
| 15 | RS2050257 | 0.394 | 0.879 | 277 | A | 38.3 | 217 | A | 34.8 |
| 16 | RS4743299 | 0.167 | 1.239 | 282 | T | 25.5 | 222 | T | 28.4 |
| 17 | RS4743300 | 0.759 | 1.045 | 279 | T | 35.1 | 222 | T | 35.4 |
| 18 | RS882727 | 0.445 | 0.851 | 279 | A | 13.6 | 220 | A | 13.2 |
| 19 | RS882728 | 0.992 | 1.002 | 281 | G | 26.2 | 221 | G | 25.1 |
| 20 | RS10819537 | 0.305 | 1.176 | 282 | T | 27.5 | 220 | T | 29.8 |
| 21 | RS1572136 | 0.507 | 1.108 | 276 | C | 28.3 | 220 | C | 29.3 |
| 22 | RS7027650 | 0.840 | 0.971 | 280 | T | 39.8 | 221 | T | 38.5 |
| 23 | RS4743301 | 0.736 | 1.090 | 280 | T | 8.4 | 220 | T | 8.6 |
| 24 | RS989392 | 0.495 | 1.134 | 280 | A | 16.4 | 222 | A | 17.3 |
| 25 | RS2416664 | 0.943 | 0.985 | 278 | T | 12.4 | 221 | T | 12.2 |
| 26 | RS3780622 | 0.374 | 0.860 | 283 | C | 22.3 | 221 | C | 19.9 |
| 27 | RS1889268 | 0.629 | 0.928 | 280 | C | 32.7 | 219 | C | 30.1 |
| 28 | RS10819587 | 0.327 | 0.787 | 277 | A | 10.8 | 220 | A | 9.1 |
| 29 | RS1041631 | 0.430 | 0.856 | 282 | A | 16.5 | 220 | A | 14.5 |
| 30 | RS12352939 | 0.674 | 1.096 | 279 | T | 11.1 | 222 | T | 11.9 |
| 31 | RS7028686 | 0.652 | 1.088 | 280 | G | 14.6 | 221 | G | 15.4 |
| 32 | RS4742755 | 0.563 | 0.883 | 281 | G | 13.3 | 221 | G | 12.9 |
| 33 | RS12684946 | 0.085 | 0.637 | 280 | A | 9.1 | 221 | A | 7.0 |
| 34 | RS17711860 | 0.514 | 1.137 | 283 | G | 13.4 | 220 | G | 14.1 |
| 35 | RS869776 | 0.496 | 0.889 | 278 | G | 23.9 | 219 | G | 22.6 |
| 36 | RS12352174 | 0.528 | 1.134 | 282 | G | 14.4 | 220 | G | 15.0 |
| 37 | RS12216916 | 0.323 | 0.800 | 280 | T | 12.0 | 221 | T | 10.0 |
| 38 | RS4142986 | 0.017 | 1.434 | 280 | C | 30.5 | 219 | C | 37.0 |
| 39 | RS11789689 | 0.108 | 0.689 | 282 | A | 11.3 | 222 | A | 9.7 |
| 40 | RS7047475 | 0.305 | 0.827 | 280 | G | 21.1 | 221 | G | 19.5 |
| 41 | RS1413298 | 0.052 | 0.738 | 281 | C | 32.7 | 221 | C | 27.4 |
| 42 | RS7040869 | 0.827 | 0.954 | 281 | A | 13.9 | 219 | A | 13.2 |
Bold indicates significantly associated SNP.