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. 2013 Nov 27;8(11):e79324. doi: 10.1371/journal.pone.0079324

Table 3. Levels of the areas under the curves for the tested variables, standard deviation and the p-value when comparing with the low-fat (control) group at the same time period (Wilcoxon Signed Ranks Test).

Variable Diet Area under curve
SD P
Glucose Low-fat 90 26
(mmol/l) Low-carb 75 21 <0.0005
Mediterranean 80 17 0.001
Insulin Low-fat 2555 2328
(pmol/l) Low-carb 1609 1396 <0.0005
Mediterranean 2425 1766 0.841
Triglycerides Low-fat 14 5
(mmol/l) Low-carb 16 7 0.014
Mediterranean 13 5 0.276
Cholesterol Low-fat 39 9
(mmol/l) Low-carb 39 8 0.121
Mediterranean 39 9 0.705
HDL-cholesterol Low-fat 12 4
(mmol/l) Low-carb 13 4 0.055
Mediterranean 12 4 0.897
LDL-cholesterol Low-fat 20 8
(mmol/l) Low-carb 20 7 0.199
Mediterranean 21 8 0.670
GIP Low-fat 26319 13081
(pg/ml) Low-carb 25680 11752 0.879
Mediterranean 24727 8885 0.215
Leptin Low-fat 16758 11611
(pg/ml) Low-carb 15874 12684 0.557
Mediterranean 13822 11187 0.001

A p-value of <0.0063 was considered statistically significant.

Abbreviations, Low-carb., low-carbohydrate diet; GIP, glucose-dependent insulinotropic polypeptide; SD, standard deviation.