Table 2. Blood indices to assess for hepatorenal toxicity of IC2B.

	Normoxic	Hypoxic	Hypoxic + CPP
Alkaline Phosphatase	179 + 20	195 + 31	176 + 16
ALT	25 + 4	30 + 10	33 + 6
AST	48 + 3	73 + 8 *	81 + 8 *
Creatine Kinase	163 + 46	236 + 90	225 + 38
GGT	2.0 + 0.0	3.0 + 0.0	2.4 + 0.6
Albumin	2.9 + 0.1	2.9 + 0.2	2.8 + 0.1
Total Protein	5.6 + 0.2	5.2 + 0.2	5.0 + 0.1
Total Bilirubin	0.1 + 0.0	0.1 + 0.0	0.1 + 0.0
Blood Urea Nitrogen	18.8 + 2.8	26.3 + 8.4	20.0 + 2.2

Abbreviations: ALT = alanine aminotransferase; AST = aspartate aminotransaminase; GGT = gamma glutamyl transpeptidase. *p < 0.05 vs normoxic.