Effect of CD11a polymorphisms on L major infection. A, Footpad swelling of WT compared with congenic mice infected with L major promastigotes. *P < .001 (n = 5 per group). B-E, Parasite burdens from footpads and spleens at 3 (Fig 2, B and D) and 6 (Fig 2, C and E) weeks. *P < .05. F, Ratio of IL-4– and IFN-γ–producing cells from popliteal lymph nodes at 3 and 6 weeks. *P < .05. G, Ratio of found in inflammatory zone1(Fizz1)/inducible nitric oxide synthase (iNOS), as assessed by using real-time quantitative PCR.*P<.05.