Table 1.

Select examples of RNA / protein abundance of iron-dependent proteins in response to iron and carbon status [24,26].

Cofactor	Gene Name	Fold- change limited + acetate1	Fold- change limited – acetate1	Protein abundance (zmol/cell) replete2	Protein abundance (zmol/cell) limited2
involved in anaerobic metabolism / down-reg. by Fe-limiting photoheterotrophic growth
[4Fe-4S]	HCP4	0.01
[4Fe-4S]	HCP1	0.04
[4Fe-4S]	PFR1	0.07
[2Fe-2S]	HYDG	0.07
[4Fe-4S]	HYDEF	0.09
[4Fe-4S]	SIR1	0.17
down-reg. in both iron-limited photoheterotrophic and photo autotrophic g rowth
[4Fe-4S]	HCP4	0.01	0.27
[4Fe-4S]	HCP1	0.04	0.28
[4Fe-4S]	SIR1	0.17	0.50
heme	truncated hemoglobin	0.03	0.06
Fe, [2Fe-2S]	glutaredoxin	0.33	0.35
heme	CYP747A1	0.35	0.21
Fe	RBD2	0.38	0.33
correlated reduction in transcript and protein abundance
[3Fe-4S]	GSN1	0.34		46 ± 10	13 ± 2
[2Fe-2S]	MitoNEET-like	0.36		37 ± 15	nd
[4Fe-4S]	ACH1	0.49		379 ± 25	280 ± 35
[4Fe-4S]	APR1	0.66		132 ± 13	32 ± 14
[4Fe-4S]	HCP3	0.30		11 ± 6	nd
[2Fe-2S]	PETF	0.61		87 ± 35	nd
reduction in protein abundance without significance change in transcript abundance
heme	APX4	1.10		26 ± 3	nd
[4Fe-4S]	IDS1	1.07		61 ± 7	nd
Fe	Cre07.g320900	0.83		351 ± 68	nd
[4Fe-4S]	LEU1L	1.12		159 ± 18	54 ± 1

¹Fold-change of RPKMs from iron-limited cultures (0.25 µM Fe) relative to cultures grown in the replete condition (20 µM Fe).

²Protein abundance was quantitated for acetate-grown cultures.