Table 4.

Clinical details by patient and group

Group	Patient	History
F+Binf	8	E. coli meningitis at day of life 10 treated with 21 days of antibiotics, Stage 3 NEC at 6 weeks of age requiring bowel resection and ileostomy. Enrolled in this trial at 2 months of age.* During the study had three additional brief courses of antibiotics (2 days during week 1, 3 days during week 2, and 4 days during week 4) while awaiting culture results. Probiotic continued throughout. Dose 3 was continued for an extra week.
F+Binf	29	Received 13 days of antibiotics for staphylococcal sepsis/pneumonia during weeks 3 and 4 with the probiotic continued throughout (dose 3 was continued during this time).
F+Binf	37	Treated with 7 days antibiotics for S. aureus pneumonia during week 1 with the probiotic dose continued throughout.
F+Blac	7	Received azidothymidine from birth until 6 weeks of age followed by trimethoprim-sulfamethoxazole (TMP-SMX) each Monday, Wednesday and Friday for another three weeks due to maternal HIV positivity. The period of participation for this infant was during the three weeks of TMP-SMX (seven “antibiotic days” were counted for each week of TMP-SMX administration).
H+Binf/Blac	44	Completed a 2 day course of antibiotics on the day of enrollment
H+Blac/Binf	45	Received 10 days of antibiotics for NEC during the first 2 weeks of the study (probiotics were held for the 10 day period of treatment)
H+Blac/Binf	47	Received 7 days of antibiotics during week 1 of the study (probiotics continued)
H+Blac/Binf	48	Received 3 days of antibiotics during week 2 of the study (probiotics continued)

^*For this patient only, ileostomy output samples rather than feces were analyzed.