Figure 7.

Granule cell migration in Abl/Arg CNS-DKO mice. A, B, Normal granule cell migration before the extensive loss of the BM in Abl/Arg CNS-DKO mice. P6 mice were injected with BrdU and killed 4 d later, and their cerebellar sections were then stained with a BrdU antibody (A, B). C–F, Normal interaction between migrating granule cell and Bergmann glial fiber in the DKO mice. C, D, Pax6 and GFAP costaining of P10 cerebellar sections. E, F, Pax6 and GFAP costaining of cerebellar cell cultures derived from the control (CTR) and DKO mice. Scale bars: (in B, C, F) A–F, 20 μm.