Table 1. The Calculated Ratios of IgG2a/IgG1 Antibody Subclasses and IFNγ/IL-4 Cytokines in Immunized Mice Groups. Indicated Ratios for HCVcp + BCG Immunogen Formulation Compared to That of HCVcp + F127 Suggested Relatively Higher Th1-Oriented Immune Responses for the Preceding Formulation.
| Groups of Immunized Mice | IgG2a /IgG1 Ratio | IFNγ/IL-4 Ratio |
|---|---|---|
| Saline | NAa | NA |
| BCG a | NA | NA |
| HCVcp a + BCG | 0.36 | 8.25 |
| F127 | NA | NA |
| HCVcp + F127 | 0.22 | 2.45 |
a Abbreviations: BCG, bacillus calmette-guerin; HCVcp, HCV core protein; NA, Not Applicable