Table 1.

IC₅₀ values for inhibition of nAChR subtypes by various α-conotoxins and their analogs (adapted from Hone etal., 2012).

	α3β2	α3β4	α4β2	α4β4	α6/α3β2β3	α6β4	α7
ArIB[V11L;V16D]	>20 μM	>20 μM	>20 μM	>20 μM	>20 μM	>20 μM	1.1 nM
BuIA	5.7 nM	27.7 nM	>10 μM	69.9 nM	258 pM	1.5 nM	272 nM
BuIA[T5A;P6O]	>10 μM	1.2 μM	>10 μM	>10 μM	>10 μM	58.1 nM	>10 μM
AuIB	>100 μM	750 nM	>100 μM	>100 μM	>100 μM	7.3 μM	~10 μM