Table 2.
Percentages of the total population of mouse and rat DRG neurons that exhibited functional expression of different nAChR subtypes.
| Mouse |
Rat |
|||||
|---|---|---|---|---|---|---|
| P14 | P20–30 | P42 | P15–17 | P30–40 | P52 | |
| % α7+ only | 11 | 7 | 14 | 20 | 35 | 27 |
| % β4+ only | 8 | 6 | 9 | 34 | 31 | 36 |
| % α7+ and β4+ | 3 | 2 | 5 | 15 | 12 | 10 |
| % ACh unresponsive | 78 | 85 | 72 | 31 | 22 | 27 |
“P” refers to the age of animals in postnatal days. For each age category of mouse or rat (each column in the table), the percentages of DRG neurons were calculated from ≤9 independent experimental trials that encompassed >600 total neurons (cells responsive to depolarization by high extracellular potassium concentration) in each case (each column).