Table 3.
Average percentages of neurons responsive to 300 nM capsaicin and their average cross-sectional cell areas (cell size) within different mature DRG neuronal subclasses defined by functional nAChR expression.
| Mouse (>P40) |
Rat (>P47) |
|||
|---|---|---|---|---|
| DRG neuronal subclass | Average % capsaicin sensitive | Average cell size (μm2) | Average % capsaicin sensitive | Average cell size (μm2) |
| α7+ only | 44% | 350 | 94% | 396 |
| β4+ only | 56% | 334 | 36% | 410 |
| α7+ & β4+ | 45% | 392 | 79% | 527 |
| ACh unresponsive | 43% | 244 | 77% | 380 |
“P” refers to the age of animals in postnatal days. Mouse data was compiled from 10 independent experimental trials that encompassed >700 total neurons (cells responsive to depolarization by high extracellular potassium concentration). Rat data was compiled from eight independent experimental trials that encompassed >600 total neurons.