. Author manuscript; available in PMC: 2013 Nov 28.

Published in final edited form as: Int J Cancer. 2008 Jun 1;122(11):10.1002/ijc.23431. doi: 10.1002/ijc.23431

TABLE II.

REGULATION OF MMP GENES DUE TO COCULTURE OF PC3 AND BMS (PC3/BMS) CELLS ON TYPE I COLLAGEN

Gene	Fold increase in mRNA
Gene	PC3/BMS vs. PC3	PC3/BMS vs. BMS
A. Microarray analysis
MMP-1	2.5	2.1
MMP-2	445.7	−2.3
MMP-3	119.4	36.8
MMP-9	NC	2.3
MMP-10	2	6.5
MMP-12	315.2	36.8
MMP-13	6.1	2.6
MMP-14	3.2	2.1
B. RT-PCR analysis
MMP-1	4.2	3.2
MMP-2	26467	0.2
MMP-3	246.9	87.3
MMP-9	1.1	2.7
MMP-10	2.3	14.2
MMP-12	1000	269.7
MMP-13	9.7	4.1
MMP-14	2.0	0.5

Fold increased in mRNA of PC3/BMS relative to PC3 or BMS cells cultured alone, as determined using gene microarray (A) and RT-PCR (B) analyses. NC, no change.