Table 2.
Phospho-kinases correlated with radiosensitivity in HNSCC
| Phospho-kinase | Condition | Spearman correlation coefficient | P-value |
|---|---|---|---|
| Src(Y419) |
Expression in control |
0.67 |
0.049 |
| Expression after RT |
0.75 |
0.019 |
|
| STAT5A(Y699) |
Expression in control |
0.70 |
0.036 |
| Yes(Y426) |
Expression in control |
0.67 |
0.050 |
| AKT(S437) |
Relative expression after RT |
0.67 |
0.050 |
| MSK1/2(S376/S360) |
Expression after RT |
0.67 |
0.050 |
| Lyn(Y397) |
Expression after RT |
0.70 |
0.036 |
| Fyn(Y420) |
Expression after RT |
0.70 |
0.036 |
| Hck(Y411) |
Expression after RT |
0.72 |
0.030 |
| STAT6(Y641) | Expression after RT | 0.67 | 0.050 |
RT: 4 Gy of radiotherapy.
Expression in control or after RT: absolute expression level in control or 1 h after RT.
Relative expression after RT: expression after radiotherapy divided by expression in control.