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The effect of ARA290 on markers of renal function. Early ARA290 treatment significantly reduced serum creatinine levels at three days post-reperfusion. Late- and repetitive ARA290 treatment tended to reduce serum creatinine levels to a lesser extent (A, p < 0.05). The treatment effect of ARA290 on serum urea levels showed the same tendency as the effect on serum creatinine levels (B).
