Table 3.
Chemical–disease profiles from CTD
| Disease terma | Toxicity profile name | No. chemicals (M-type)b | No. diseases | Therapeutic profile name | No. chemicals (T-type)b | No. diseases |
|---|---|---|---|---|---|---|
| Cardiovascular diseases | CardioTox | 1 847 | 305 | CardioTreat | 1 543 | 231 |
| Nervous system diseases | NeuroTox | 2 533 | 522 | NeuroTreat | 2 216 | 476 |
| Liver diseases | HepatoTox | 1 275 | 55 | HepatoTreat | 635 | 56 |
| Kidney diseases | RenalTox | 1 047 | 64 | RenalTreat | 528 | 62 |
| Skin diseases | SkinTox | 1 145 | 146 | SkinTreat | 667 | 165 |
| Neoplasms | CancerTox | 1 007 | 240 | CancerTreat | 1 516 | 312 |
| Immune system diseases | ImmunoTox | 982 | 126 | ImmunoTreat | 720 | 141 |
| Respiratory tract diseases | LungTox | 945 | 132 | LungTreat | 706 | 116 |
| Metabolic diseases | MetaboloTox | 855 | 142 | MetaboloTreat | 535 | 140 |
| Hematologic diseases | HematoTox | 822 | 98 | HematoTreat | 313 | 82 |
| Gastrointestinal diseases | GastroTox | 583 | 88 | GastroTreat | 538 | 82 |
| Eye diseases | EyeTox | 542 | 129 | EyeTreat | 281 | 107 |
| Endocrine system diseases | EndoTox | 522 | 89 | EndoTreat | 530 | 90 |
| Muscular diseases | MuscleTox | 497 | 46 | MuscleTreat | 198 | 33 |
| Lymphatic diseases | LymphaTox | 197 | 43 | LymphaTreat | 295 | 52 |
| Bone diseases | BoneTox | 148 | 49 | BoneTreat | 184 | 48 |
| Connective tissue diseases | ConnectiTox | 122 | 25 | ConnectiTreat | 166 | 40 |
aInput term used to retrieve data using CTD's Batch Query tool.
bM, marker/mechansim-type relationship (for –Tox files); T, therapeutic-type relationship (for -Treat files).