Table A2.

RRs and 95% CIs for Neurocognitive Impairment by CRT and Age at Diagnosis

Age at Diagnosis (years)	CRT (Gy)	Intelligence		Academic		Memory
		RR	95% CI	RR	95% CI	RR	95% CI
1	18	1.44	0.51 to 4.08	5.75	1.50 to 22.01	1.94	0.89 to 4.23
	24	5.85	2.47 to 13.83	6.99	2.03 to 24.04	4.42	2.22 to 8.82
2	18	1.42	0.55 to 3.64	4.06	1.31 to 12.63	1.84	0.92 to 3.70
	24	5.16	2.39 to 11.13	5.70	1.96 to 16.62	3.88	2.10. 7.16
3	18	1.40	0.60 to 3.27	2.87	1.08 to 7.63	1.75	0.94 to 3.26
	24	4.55	2.29 to 9.03	4.65	1.84 to 11.75	3.40	1.97 to 5.86
4	18	1.38	0.65 to 2.96	2.03	0.83 to 5.00	1.65	0.94 to 2.90
	24	4.02	2.18 to 7.40	3.80	1.68 to 8.59	2.98	1.83 to 4.86
5	18	1.36	0.69 to 2.71	1.44	0.57 to 3.62	1.57	0.94 to 2.62
	24	3.54	2.04 to 6.16	3.10	1.45 to 6.60	2.62	1.67 to 4.10
6	18	1.35	0.72 to 2.52	1.02	0.36 to 2.87	1.49	0.92 to 2.41
	24	3.13	1.87 to 5.23	2.53	1.19 to 5.38	2.30	1.49 to 3.54
7	18	1.33	0.73 to 2.40	0.72	0.21 to 2.44	1.41	0.88 to 2.27
	24	2.76	1.67 to 4.56	2.06	0.91 to 4.67	2.01	1.29 to 3.14
8	18	1.31	0.73 to 2.34	0.51	0.12 to 2.16	1.34	0.82 to 2.19
	24	2.43	1.45 to 4.08	1.68	0.67 to 4.25	1.77	1.10 to 2.84
9	18	1.29	0.71 to 2.34	0.36	0.07 to 1.96	1.27	0.75 to 2.15
	24	2.15	1.23 to 3.74	1.37	0.47 to 4.00	1.55	0.91 to 2.62
10	18	1.27	0.67 to 2.41	0.25	0.04 to 1.81	1.20	0.67 to 2.16
	24	1.90	1.03 to 3.50	1.12	0.33 to 3.86	1.36	0.75 to 2.46

NOTE. Risk associated with CRT is referenced to no-CRT group.

Abbreviations: CRT, cranial radiation therapy; RR, relative risk.