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. 2013 Nov 28;8(11):e81752. doi: 10.1371/journal.pone.0081752

Figure 4. Experimental sepsis in OVA-immunized mice reduces OVA-specific serum IgG.

Figure 4

OVA-specific serum-IgM and -IgG at 2 and 4 wk after CASP (colon ascendens stent peritonitis) are shown here (au = arbitrary units). C57BL/6 mice were immunized and boosted with OVA at 6 and 9 wk, respectively, and CASP was induced 8 wk after the secondary immunization. Control animals were either untreated, only immunized or only CASP induced. A combination of two independent experiments with the same trend is shown here. A statistical analysis was performed with the one-way ANOVA and Bonferroni’s post test for selected pairs.

n=10-18/group. *: p<0.05; **: p<0.01.