Figure 5. Spontaneous gliotransmission is altered in Tg2576.

A. Patch clamp recording from a CA1 pyramidal neuron from a WT littermate, illustrating spontaneous SIC incidence. Two exemplar SICs are shown expanded beneath. Also shown is a recording from a Tg2576 hippocampal slice with expanded SICs illustrated beneath. B. Cumulative probability distributions of SIC parameters frequency, rise time, duration and charge (Q) for WT (black lines) and Tg2576 (dark grey lines).