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. Author manuscript; available in PMC: 2013 Nov 28.
Published in final edited form as: Neuroimage. 2013 Apr 13;78:68–74. doi: 10.1016/j.neuroimage.2013.04.022

Table 4.

Correlation between susceptibility mapping and iron concentration.

Authors Correlation slopea Structures Background removal QSM methodb Myelin correction Field (Tesla) Sample Iron
This paper 1.11 N.A. Quadratic fitting Forward fitting N.A. 3 T Ferritin ICPMS
This paper 1.10 N.A. Quadratic fitting Forward fitting N.A. 3 T Ferritin XRF
This paper 0.80 GP, PUT, CN SHARP TKD1 (SO) No 3 T MS cadaveric brain (fixed) XRF
Haacke (2012) 0.59 GP, PUT, CN SHARP TKD1 (SO) No 3 T In vivo brains H&Sc
Shmueli et al. (2009) 0.56 PUT, RN, SN Polynomial fitting TKD2 (SO) No 7 T In vivo brain H&S
Wharton and Bowtell (2010) 0.75/0.6 GP, SN, RN, PUT, CN, TH, GM Simulated geometric effect + fitting TKD3 (MO/SO) No 7 T In vivo brains H&S
Langkammer et al. (2012a) 0.89 GP, PUT, CN, TH SHARP HEIDI (SO) No 3 T Unfixed cadaveric brains ICPMS
Schweser et al. (2011) 1.30 GP, SN, DN, PUT, CN, TH, WM, GM SHARP MO regularization Yes 3 T In vivo brains H&S
a

The unit of the slope for human brain is susceptibility/μg iron/g wet tissue (ρ = 1.04g/ml at 36.5 °C); the unit of the slope for the ferritin solution is ppb susceptibility/μg iron/ml and the corresponding theoretical value is 1.27.

b

SO: single orientation; MO: multiple orientation; TKD: thresholded k-space division. TKD1: Haacke et al., 2010; TKD2: Shmueli et al., 2009; TKD3: (Wharton and Bowtell, 2010).