Fig. 8.
Proposed gene network illustrating the most likely position of Maturin in the proneural pathway. Maturin and Pak3 function together downstream of the proneural transcription factors to promote differentiation of the primary neurons. Our results are consistent with models in which Maturin and Pak3 form a complex (A), or function independently (B). In both models, Maturin and Pak3 are both required for normal primary neurogenesis.