FIGURE 4.
Cysteine racemization on IgG1λ HC. a, XIC of peptides and isotopic distribution (inset). The y axis of the inset represents relative level. Top panel, unstressed material. Second panel from top, antibody was incubated at 56 °C for 6 days at pH 9.3 in D2O. Third panel from top, synthetic peptide S(l-C)DK (l-H). Bottom panel, synthetic peptide S(d-C)DK (d-H). b, MS2 spectra of selected peaks shown in a.