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. 2013 Oct 10;288(48):34658–34670. doi: 10.1074/jbc.M113.500314

TABLE 1.

Wnt/β-catenin inhibitors that are regulated by WNT3A

For each of the listed gene symbols, the peptide sequences and fold changes in phosphopeptide abundance that were observed in the quantitative phosphoproteomics experiments are listed. Phosphorylation modifications are denoted with asterisks. A dash (—) indicates experiments where the listed peptide was not identified. Additionally, the -fold changes observed for the listed gene symbols in the siRNA screen are given. WNT3A-60, WNT3A stimulation for 60 min; WNT3A-240, WNT3A stimulation for 240 min.

Gene symbol Peptide log2 fold
WNT3A-60 WNT3A-240 siRNA screen
MAP3K3 LRS*ADS*ENALSVQER 4.72 −0.29 6.63
PIK3CA S*MLLSSEQLK 3.89 5.16
PKN1 LIPNATGTGTFS*PGAS*PGSEAR −2.84 −0.07 3.45
STK4 AIHKET*GQIVAIK −3.47 7.92