Table 4.
Comparison of previous case–control studies with the present study
| Polymorphism | Present study | Walch et al. | Erdogan et al. | ||||||
|---|---|---|---|---|---|---|---|---|---|
| −174 G/C | PCOS n = 104 (%) | Controls n = 156 (%) | p-value/odds ratio | PCOS n = 62 (%) | Controls n = 94(%) | p-value/odds ratio | PCOS n =88 (%) | Controls n = 119 (%) | p-value/odds ratio |
| Genotypes | |||||||||
| C/C | 4 (3.8) | 6 (3.8) | 0.02 | 8 (38.7) | 16 (45.7) | 0.48 | 5 (5.7) | 12(10.1) | < 0.001 |
| G/C | 31 (29.8) | 73 (46.8) | 30 (48.4) | 35 (37.2) | 26 (29.5) | 75(63.0) | |||
| G/G | 69 (66.3) | 77 (49.4) | 24 (36.2) | 43 (28.6) | 57 (64.8) | 32 (26.9) | |||
| Alleles | |||||||||
| C | 39 (18.75) | 85 (27.2) | 0.0259/1.6226 | 46 (37.1) | 67 (35.6) | 0.89/1.1 | 30 (20.5) | 99(41.6) | < 0.001 |
| G | 169 (81.25) | 227 (72.8) | 78 (62.9) | 121 (64.4) | 146 (79.5) | 139(58.4) | |||