Skip to main content
. 2013 Nov 15;6(12):2765–2777.

Figure 4.

Figure 4

Ki-67 immunohistochemical staining in cHL. A&B: Showing nuclear immunoreactivity of H/RS cells (thick arrows) to ki-67 in EBV+ve and EBV-ve HL respectively. Some adjacent lymphocytes show immunoreactivity to ki-67 too (arrow head). There is significant increase in ki-67 positive H/RS cells (thick arrows) in EBV+ve HL. Streptavidin-biotin immunoperoxidase method. C&D: Showing nuclear immunoreactivity of H/RS cells (thick arrows) to ki-67 in COX2+ve and COX2-ve HL respectively. Some adjacent lymphocytes show immunoreactivity to ki-67 too (arrow head). There is no significant difference in ki-67 positive H/RS cells (thick arrows) between COX2+ve and COX2-ve HL. Streptavidin-biotin immunoperoxidase method. E&F: Showing nuclear immunoreactivity of H/RS cells (thick arrows) to ki-67 in p16+ve and p16-ve HL respectively. Some adjacent lymphocytes show immunoreactivity to ki-67 too (arrow head). There is no significant difference in ki-67 positive H/RS cells (thick arrows) between p16+ve and p16-ve HL. Streptavidin-biotin immunoperoxidase method. G&H: Showing nuclear immunoreactivity of H/RS cells (thick arrows) to ki-67 in p53+ve and p53-ve HL respectively. Some adjacent lymphocytes show immunoreactivity to ki-67 too (arrow head). There is significant increase in ki-67 positive H/RS cells (thick arrows) in p53+ve HL. Streptavidin-biotin immunoperoxidase method.