Table 1.
Clinicopathologic characteristics of patients including the result of EGFR mutation testing
| Characteristics | All patients | Patients with EGFR mutation | Patients with EGFR wild type |
|---|---|---|---|
| Subjects | 273 | 29 (10.6%) | 244 (89.4%) |
| Sex | |||
| Male | 151 (55.3%) | 7 (24.2%) | 144 (59%) |
| Female | 122 (44.7%) | 22 (75.8%) | 100 (41%) |
| Age (years; range) | 61.5 (25-84) | 63.5 (40-77) | 61.2 (25-84) |
| Male | 61.9 (25-84) | 62.9 (53-77) | 61.9 (25-84) |
| Female | 60.9 (37-82) | 63.8 (40-77) | 60.3 (37-82) |
| Type of material | |||
| Histological | 189 (69.2%) | 18 (62.1%) | 171 (70.1%) |
| Cytological | 84 (30.8%) | 11 (37.9%) | 73 (29.9%) |
| [fixed/fresh] | [72 (26.4%)/12 (4.4%)] | [8 (27.6%)/3 (10.3%)] | [64 (26.2%)/9 (3.7%)] |
| Histological type | |||
| Adenocarcinoma | 186 (68.1%) | 26 (89.8%) | 160 (65.6%) |
| Squamous cell carcinoma | 44 (16.1%) | 2 (6.8%) | 42 (17.2%) |
| Adenosquamous | 4 (1.5%) | 0 | 4 (1.6%) |
| Large cell carcinoma | 9 (3.3%) | 0 | 9 (3.7%) |
| NSCLC, NOS* | 30 (11%) | 1 (3.4%) | 29 (11.9%) |
| EGFR gene copy number# | 110 | 6 | 104 |
| FISH positive | 33 (30%) | 4 (66.6%) | 29 (27.8%) |
| FISH negative | 77 (70%) | 2 (33.4%) | 75 (72.2%) |
*
Not-otherwise specified.
#
Available only for histological samples.