Figure 4.

MiR-195 down-regulates the expression of survivin, MMP9, up-regulates the expression of CD82, tissue inhibitor of TIMP1 and TIMP2 of eutopic ESCs by targeting FKN. A: In-cell Western blot was used to analyze the expression of survivin, CD82, PCNA. B: In-cell Western assays were conducted to analyze the expression of MMP2, MMP9, TIMP1, and TIMP2. Survivin, CD82, MMP2, MMP9, TIMP1, and TIMP2: Red; actin: green. These pictures are representatives of three individual experiments. Error bars depict the standard error of the mean. *P<0.05, **P<0.01 compared with the vehicle control. #P<0.05, ##P<0.01 compared with the miR-195 treatment.