Table 2.
Univariate and multivariate analysis of prognostic factors in NSCLC for 5-year overall survival
| Characteristic | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| HR | P | 95% CI | HR | P | 95% CI | |||
| ZO-1 expression | ||||||||
| High vs low | 0.188 | <0.001 | 0.109 | 0.326 | 0.281 | <0.001* | 0.169 | 0.466 |
| Gender | ||||||||
| Male vs Female | 1.302 | 0.329 | 0.766 | 2.212 | ||||
| Age (years) | ||||||||
| ≤60 vs >60 | 1.643 | 0.053 | 0.993 | 2.719 | ||||
| Diameter (cm) | ||||||||
| ≤3 vs >3 | 1.373 | 0.235 | 0.814 | 2.318 | ||||
| Histological type | ||||||||
| Sq vs Ad | .987 | 0.956 | 0.628 | 1.552 | ||||
| Differentiation | ||||||||
| Well vs Moderate vs Poorly | 1.364 | 0.154 | 0.890 | 2.092 | ||||
| Lymph node metastasis | ||||||||
| No metastasis vs metastasis | 1.201 | 0.200 | 0.906 | 1.604 | .070 | 0.025* | .007 | 0.712 |
| Stage | ||||||||
| I vs II vs III-IV | 1.312 | 0.060 | .989 | 1.740 | 13.065 | 0.031* | 1.265 | 134.6 |
*
P<0.05.