Table 1.

Predictors of poor outcome (OHS 3-6) three years after lacunar or mild cortical stroke

	Univariate			Multivariate
Variable	OR/unit increase	95% CI	P value	OR (95% CI)/ unit increase	P value
Age (per year)	1.09	1.03-1.17	0.007
Male	1.50	0.4-6.2	0.5
Hypertension y/n	1.00	0.3-3.1	1.0
Diabetes y/n	1.50	0.3-6.7	0.6
Cortical v lacunar stroke	1.67	0.55-5.05	0.364
Baseline NIHSS	1.10	0.7-1.9	0.6
Cortical grey permeability	1.30	0.6-2.7	0.5	1.37 (0.61–3.10)*	0.4
Basal ganglia permeability	2.10	1.1-4.3	0.027	2.15 (1.01-4.57)*	0.046
White matter permeability	0.9	0.2-5.5	0.9	1.5 (0.19–11.8)*	0.7
CSF permeability	0.8	0.6-1.0	0.06	0.8 (0.6–1.1) *	0.2
Fazekas DWMH score (0-3)	3.91	1.82-8.39	<0.001	3.3 (1.4-7.5)#	0.005
Fazekas PVWMH score (0-3)	4.09	1.90-8.78	<0.001	3.5 (1.4-8.6)#	0.006
Fazekas WMH combined score (0-6)	4.50	2.0-10.0	<0.001	4.8 (2.0-11.4)* + 4.1 (1.6-10.3)# +	<0.001

^*=corrected for baseline WMH;

^#=corrected for age;

⁺per unit increase in WMH