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. Author manuscript; available in PMC: 2014 Nov 15.
Published in final edited form as: Clin Cancer Res. 2013 Sep 17;19(22):10.1158/1078-0432.CCR-13-0145. doi: 10.1158/1078-0432.CCR-13-0145

Figure 1.

Figure 1

Proliferative effects on 13 CRC cell lines plotted as IC50 following exposure to (A) OSI-906 (0–5 μmol/L), or (B) U0126 (0–20 μmol/L). In the OSI-906 graph, green and red bars represent sensitive (IC50 < 1.5 μmol/L) and resistant (IC50 > 5 μmol/L) cell lines, respectively. Mutational status of KRAS, BRAF and PIK3CA of these cell lines were colored as blue boxes.