Table 6.
Biology process terms regulated by the miRNA-TF synergistic regulatory network
| GO term | Annotation | Rank a | In motifs b |
|---|---|---|---|
| GO:0042981 |
Regulation of apoptosis |
1 |
10 |
| GO:0032268 |
Regulation of cellular protein metabolic process |
2 |
10 |
| GO:0007167 |
Enzyme linked receptor protein signaling pathway |
3 |
9/I |
| GO:0031399 |
Regulation of protein modification process |
4 |
10 |
| GO:0042325 |
Regulation of phosphorylation |
5 |
10 |
| GO:0019220 |
Regulation of phosphate metabolic process |
6 |
10 |
| GO:0051329 |
Interface of mitotic cell cycle |
7 |
10 |
| GO:0000082 |
G1/S transition of mitotic cell cycle |
8 |
9/IV |
| GO:0001932 |
Regulation of protein phosphorylation |
9 |
10 |
| GO:0007169 |
Transmembrane receptor protein tyrosine kinase signaling pathway |
10 |
9/I |
| GO:0071156 |
Regulation of cell cycle arrest |
11 |
9/IV |
| GO:0045859 |
Regulation of protein kinase activity |
12 |
10 |
| GO:0000075 |
Cell cycle checkpoint |
13 |
9/IV |
| GO:0006259 |
DNA metabolic process |
14 |
10 |
| GO:0006281 |
DNA repair |
15 |
9/IV |
| GO:0043549 |
Regulation of kinase activity |
16 |
10 |
| GO:2000045 |
Regulation of G1/S transition of mitotic cell cycle |
17 |
9/IV |
| GO:0000084 |
S phase of mitotic cell cycle |
18 |
9/IV |
| GO:0051320 |
S phase |
19 |
9/IV |
| GO:0007093 |
Mitotic cell cycle checkpoint |
20 |
9/IV |
| GO:0031575 |
Mitotic cell cycle G1/S transition checkpoint |
21 |
8/III, IV |
| GO:0071779 |
G1/S transition checkpoint |
22 |
8/III, IV |
| GO:0006468 |
Protein phosphorylation |
23 |
9/I |
| GO:0043066 |
Negative regulation of apoptosis |
24 |
9/I |
| GO:0043069 |
Negative regulation of programmed cell death |
25 |
9/I |
| GO:0031328 |
Positive regulation of cellular biosynthetic process |
26 |
9/I |
| GO:0071900 |
Regulation of protein serine/threonine kinase activity |
27 |
9/I |
| GO:0009968 |
Negative regulation of signal transduction |
28 |
9/I |
| GO:0048011 |
Nerve growth factor receptor signaling pathway |
29 |
9/I |
| GO:0046777 |
Protein autophosphorylation |
30 |
7/I, II, V |
| GO:0006355 |
Regulation of transcription, DNA-dependent |
31 |
9/I |
| GO:2001141 |
Regulation of RNA biosynthetic process |
32 |
9/I |
| GO:0009967 |
Positive regulation of signal transduction |
33 |
8/I, V |
| GO:0006357 |
Regulation of transcription from RNA polymerase II promoter |
34 |
9/I |
| GO:0043065 |
Positive regulation of apoptosis |
35 |
9/I |
| GO:0045893 | Positive regulation of transcription, DNA-dependent | 36 | 8/I,III |
aRank: is the rank number calculated using the formula (2.7.1) based on the number of occurrences of the GO terms among all the assigned terms.
bIn motifs: is how many motif types (subnetworks) were assigned the corresponding GO term. The roman number(s) following the slash indicate the subnetwork(s) in which the corresponding GO term was not found.