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. 2013 Oct 31;7:112. doi: 10.1186/1752-0509-7-112

Table 3.

Significant topological bias of disease genes relative to non-disease genes

  In-degree Out-degree CC Btwn
Brain
graphic file with name 1752-0509-7-112-i35.gif
graphic file with name 1752-0509-7-112-i36.gif
graphic file with name 1752-0509-7-112-i37.gif
  
Heart
  
graphic file with name 1752-0509-7-112-i38.gif
graphic file with name 1752-0509-7-112-i39.gif
  
Kidney
graphic file with name 1752-0509-7-112-i40.gif
graphic file with name 1752-0509-7-112-i41.gif
graphic file with name 1752-0509-7-112-i42.gif
graphic file with name 1752-0509-7-112-i43.gif
Liver
graphic file with name 1752-0509-7-112-i44.gif
graphic file with name 1752-0509-7-112-i45.gif
graphic file with name 1752-0509-7-112-i46.gif
graphic file with name 1752-0509-7-112-i47.gif
Ovary
  
graphic file with name 1752-0509-7-112-i48.gif
graphic file with name 1752-0509-7-112-i49.gif
graphic file with name 1752-0509-7-112-i50.gif
Spleen
  
graphic file with name 1752-0509-7-112-i51.gif
graphic file with name 1752-0509-7-112-i52.gif
  
Testis
graphic file with name 1752-0509-7-112-i53.gif
graphic file with name 1752-0509-7-112-i54.gif
graphic file with name 1752-0509-7-112-i55.gif
graphic file with name 1752-0509-7-112-i56.gif

P < 0.10. cc: cluster coefficient; Btwn: betweenness, Red circle: disease miRNA; Green circle: disease TF.

Red circle indicates that the relative centralities of disease miRNAs are significantly higher than those of non-disease miRNAs in the corresponding tissue. Green circle indicates that the relative centralities of disease TFs are significantly higher than those of non-disease TFs in the corresponding tissue. P < 0.10.